SCHEMBL10015682

SCHEMBL10015682

C=CCNC(=O)COCF

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 2/20 0.50
TSHR P16473 2/20 0.50
RAB9A P51151 2/20 0.44
HTT P42858 2/20 0.44
GAA P10253 2/20 0.44
GLA P06280 1/20 0.44
FAAH O00519 1/20 0.42
HPGD P15428 3/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
LMNA P02545 1/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 2/20 0.37
HSD17B10 Q99714 1/20 0.36
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11769800 0.80 SMN1; SMN2 (0.50) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL14780249 0.78 SMN1; SMN2 (0.48) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL25140820 0.76
SCHEMBL8611731 0.76 SMN1; SMN2 (0.46) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL16747754 0.75
SCHEMBL5256191 0.75
Sulfuric Acid SCHEMBL14780148 0.73 SMN1; SMN2 (0.43) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL26091851 0.73 SMN1; SMN2 (0.68) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL6037951 0.72 HPGD (0.50) SMN1; SMN2MAPTTSHRRAB9AHTT
SCHEMBL1958588 0.71 SMN1; SMN2 (0.81) SMN1; SMN2MAPTTSHRRAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8805244-B2 Charging member, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-12 US disclosed
US-20120076532-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-03-29 US disclosed