Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595669 | 0.88 | NOTUM (0.48) | NOTUMPIK3CAMKNK1IMPDH2KDR | |
| SCHEMBL10016743 | 0.88 | NOTUM (0.48) | NOTUMPIK3CAMKNK1IMPDH2KDR | |
| SCHEMBL17320821 | 0.86 | CYP11B1 (0.46) | PIK3CAMKNK1MKNK2TNFDHODH | |
| SCHEMBL10017017 | 0.85 | NOTUM (0.54) | NOTUMPIK3CAMKNK1IMPDH2KDR | |
| SCHEMBL10017117 | 0.85 | NOTUM (0.52) | NOTUMPIK3CAIMPDH2KDRTNF | |
| SCHEMBL9613015 | 0.84 | PIK3CA (0.51) | NOTUMPIK3CAACVR1MKNK1IMPDH2 | |
| SCHEMBL18174777 | 0.83 | CYP2A6 (0.40) | PIK3CAACVR1IMPDH2KDRPDGFRB | |
| SCHEMBL17320820 | 0.82 | KDM4E (0.46) | PDGFRBPDGFRATNFDHODHALOX5 | |
| SCHEMBL13978952 | 0.82 | NOTUM (0.48) | NOTUMIMPDH2DHODHKDM4EALDH1A1 | |
| SCHEMBL17320831 | 0.81 | PDGFRB (0.41) | PDGFRBPDGFRATNFDHODHCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005214-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | JNC株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |