SCHEMBL18174777

SCHEMBL18174777

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5)c5ccccc45)c4ccccc34)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
PIK3CA P42336 2/20 0.39
IMPDH2 P12268 3/20 0.38
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
KDR P35968 1/20 0.36
MAPK10 P53779 1/20 0.36
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
MAPK14 Q16539 1/20 0.34
DHODH Q02127 2/20 0.34
MAPK1 P28482 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612943 0.92 CYP2A6 (0.39) CYP2A6MEN1KMT2AS1PR1S1PR3
SCHEMBL18174764 0.92 CYP2A6 (0.41) CYP2A6S1PR1S1PR3KDRCYP11B1
SCHEMBL18174747 0.92 CYP2A6 (0.46) CYP2A6PIK3CAIMPDH2MAPTNPSR1
SCHEMBL18174705 0.90 CYP2A6 (0.38) CYP2A6PIK3CAIMPDH2MAPTNPSR1
SCHEMBL18174672 0.90 CYP2A6 (0.38) CYP2A6PIK3CAIMPDH2MAPTNPSR1
SCHEMBL15161110 0.88 CYP11B1 (0.44) CYP2A6KDM4ELMNAMAPK10CYP11B1
SCHEMBL18174790 0.87 WNT3A (0.42) CYP2A6PIK3CA
SCHEMBL18174775 0.86 GRM4 (0.35) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL18174789 0.86 DHODH (0.46) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL18174760 0.86 GRM4 (0.38) CYP2A6PIK3CAS1PR1S1PR3DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed