SCHEMBL10017751

SCHEMBL10017751

NCCN(CCC=O)CCC=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.34
HIF1A Q16665 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13154520 0.91 LCK (0.39) LCKHIF1A
SCHEMBL16360416 0.87
SCHEMBL23775553 0.85 ALDH1A1 (0.36) ALDH1A1
SCHEMBL13181441 0.85 HIF1A (0.44) HIF1AALDH1A1
SCHEMBL23121423 0.84 HIF1A (0.36) LCKHIF1A
SCHEMBL13154489 0.83
SCHEMBL29168500 0.80 CHRM2 (0.41) LCKHIF1AALDH1A1
SCHEMBL13469079 0.80 LCK (0.32) LCK
SCHEMBL1062510 0.74 LCK (0.48) LCK
SCHEMBL33394 0.74 LCK (0.48) LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9198872-B2 Dendritic and hyperbranched polymers for cellular encapsulation and functionalization UNIVERSITY OF MIAMI (US) 2015-12-01 US disclosed
WO-2012017118-A1 CARBON NANOHORNS COMPRISING DENDRIMERS ON THEIR SURFACE AS NON -VIRAL VECTORS FOR GENE THERAPY UNIVERSIDAD CASTILLA LA MANCHA (50%) (ES) 2012-02-09 WO disclosed
WO-2011072627-A2 DENDRITIC HIGH-MOLECULAR-WEIGHT POLYMER DRUG CARRIERS AND THEIR CONJUGATES WITH DRUGS ESPECIALLY FOR TREATMENT OF SOLID TUMOURS USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. (CZ) 2011-06-23 WO disclosed
WO-2009110523-A2 DENDRIMER PARTICLE, MRI CONTRAST MEDIUM, AND METHOD OF MANUFACTURING A DENDRIMER PARTICLE KYOTO UNIVERSITY (JP) 2009-09-11 WO disclosed