Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658712 | 0.98 | PAOX (0.62) | PAOXHIF1AKDM4EMAPK1SIRT6 | |
| SCHEMBL16392579 | 0.81 | EPHX1 (0.52) | PAOXHIF1AKDM4EMAPK1DPP7 | |
| SCHEMBL22484276 | 0.80 | PAOX (0.50) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL13256393 | 0.80 | PAOX (0.50) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL23383701 | 0.80 | PAOX (0.54) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL18049513 | 0.80 | CA12 (0.50) | PAOXMAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL10309189 | 0.79 | EPHX1 (0.55) | PAOXHIF1AKDM4EMAPK1 | |
| SCHEMBL16392665 | 0.79 | EPHX1 (0.47) | PAOXHIF1AKDM4EMAPK1 | |
| SCHEMBL5820192 | 0.79 | KDM4E (0.43) | PAOXHIF1AKDM4EMAPK1ADRA1A | |
| SCHEMBL361286 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468718-A1 | Cabanillasin, a new antifungal compound, produced by entomopathogenic xenorhabdus cabanillasii | Nosopharm (FR) | 2012-06-27 | — | — | EP | disclosed |