Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018170 | 0.99 | HTT (0.56) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL10018169 | 0.94 | HTT (0.52) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL822849 | 0.94 | HTT (0.61) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL10034457 | 0.89 | HTT (0.61) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL12678115 | 0.87 | SYK (0.45) | HTTL3MBTL1ALDH1A1ALKBH3KDM4E | |
| SCHEMBL12585649 | 0.86 | HTT (0.50) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL9891116 | 0.86 | ALDH1A1 (0.51) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13670320 | 0.86 | HTT (0.52) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL10034487 | 0.86 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL13665720 | 0.86 | HTT (0.52) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016043-A1 | POLY(ARYLENE ETHER) COPOLYMER HAVING CATION-EXCHANGE GROUP, PROCESS OF MANUFACTURING THE SAME, AND USE THEREOF | HYUNDAI MOTOR COMPANY (KR) | 2012-01-19 | — | — | US | disclosed |
| US-8084568-B1 | Poly(arylene ether) copolymer having cation-exchange group, process of manufacturing the same, and use thereof | HYUNDAI MOTOR COMPANY (KR) | 2011-12-27 | — | — | US | disclosed |