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SCHEMBL10018730

SCHEMBL10018730

C=CC(=O)OCCCCCCCCCCCOc1ccc(C(=O)Oc2ccc(-c3ccc(CC(C)CC)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ MAPT P10636 5/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ RARB P10826 4/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ PRSS1 P07477 1/20 0.40
▸ ACR P10323 1/20 0.40
▸ HTT P42858 2/20 0.39
▸ THRB P10828 3/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9996833 1.00 SMN1; SMN2 (0.43) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL13236103 1.00 SMN1; SMN2 (0.43) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL10018726 0.97 MAPT (0.43) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL9996731 0.97 NPC1 (0.46) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL13390191 0.97 NPC1 (0.46) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL10018731 0.97 NPC1 (0.46) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL20653120 0.96 NPC1 (0.45) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL10018728 0.96 NPC1 (0.45) SMN1; SMN2NPC1LMNANFKB1NFKB2
SCHEMBL10408342 0.92 THRB (0.45) CYP3A4RARBHTTTHRBALDH1A1
SCHEMBL10409028 0.92 THRB (0.45) CYP3A4RARBHTTTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567522-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2017-02-14 — — US disclosed
US-9567522-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2017-02-14 — — US disclosed
US-20130193376-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-08-01 — — US disclosed
US-20130193376-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-08-01 — — US disclosed
US-8409469-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2013-04-02 — — US disclosed
US-8409469-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2013-04-02 — — US disclosed
US-8333906-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2012-12-18 — — US disclosed
US-8333906-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2012-12-18 — — US disclosed
US-20120012785-A1 Liquid Crystal System And Liquid Crystal Display SCHOTT CECILE (TW) 2012-01-19 — — US disclosed
US-20120012785-A1 Liquid Crystal System And Liquid Crystal Display SCHOTT CECILE (TW) 2012-01-19 — — US disclosed
US-20100258763-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY SCHOTT CECILE 2010-10-14 — — US disclosed
US-20100258763-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY SCHOTT CECILE 2010-10-14 — — US disclosed
US-7794621-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2010-09-14 — — US disclosed
US-7794621-B2 Liquid crystal system and liquid crystal display MERCK PATENT GMBH (DE) 2010-09-14 — — US disclosed
US-20090267025-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-10-29 — — US disclosed
US-20090267025-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-10-29 — — US disclosed
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