SCHEMBL10018786

SCHEMBL10018786

O=C(/N=N\C(=O)NCCN1CCNC1=O)NCCN1CCNC1=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
RAB9A P51151 1/20 0.56
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
LMNA P02545 1/20 0.53
CREBBP Q92793 1/20 0.45
FPR3 P25089 4/20 0.42
FPR2 P25090 4/20 0.42
ENPP2 Q13822 1/20 0.42
HPGDS O60760 1/20 0.41
PLAT P00750 1/20 0.39
POLR1A O95602 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363797 0.94 KMT2A (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL15167264 0.94 KMT2A (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL15187471 0.93 KMT2A (0.53) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL370153 0.93 KDM4E (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL15167554 0.93 KDM4E (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL15187472 0.89 KMT2A (0.53) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL19018103 0.88 KMT2A (0.46) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL10018803 0.87 KMT2A (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL15167550 0.87 KMT2A (0.51) KMT2ARAB9AKDM4EALDH1A1LMNA
SCHEMBL9167791 0.84 KMT2A (0.60) KMT2ARAB9AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435485-B2 Polymer modified along the chain and process for the synthesis thereof COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2019-10-08 US disclosed
EP-3172242-B1 POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF MICHELIN & CIE (FR) 2019-03-27 EP disclosed
EP-2593438-B1 MOLECULES HAVING COMBINABLE GROUPS ARKEMA FRANCE (FR) 2017-09-06 EP disclosed
US-20170174794-A1 POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-06-22 US disclosed
US-20170174794-A1 POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-06-22 US disclosed
US-9481754-B2 Graft polymer to which combined nitrogen molecules are grafted COMPAGNIE GENERALE DES ESTRABLISSEMENTS MICHELIN (FR) 2016-11-01 US disclosed
US-9481754-B2 Graft polymer to which combined nitrogen molecules are grafted COMPAGNIE GENERALE DES ESTRABLISSEMENTS MICHELIN (FR) 2016-11-01 US disclosed
WO-2016012257-A1 POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-01-28 WO disclosed
EP-2593487-B1 POLYMERS CRAFTED WITH ASSOTIATIVE AZOTIC MOLECULES MICHELIN & CIE (FR) 2015-11-25 EP disclosed
US-9073872-B2 Molecules having combinable groups ARKEMA FRANCE (FR) 2015-07-07 US disclosed
US-9073872-B2 Molecules having combinable groups ARKEMA FRANCE (FR) 2015-07-07 US disclosed
US-20140316057-A1 GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-10-23 US disclosed
US-20140316057-A1 GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-10-23 US disclosed
US-20130211057-A1 MOLECULES HAVING COMBINABLE GROUPS ARKEMA FRANCE (FR) 2013-08-15 US disclosed
US-20130211057-A1 MOLECULES HAVING COMBINABLE GROUPS ARKEMA FRANCE (FR) 2013-08-15 US disclosed
WO-2012007443-A1 GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2012-01-19 WO disclosed
WO-2012007685-A1 MOLECULES HAVING COMBINABLE GROUPS ARKEMA FRANCE (FR) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130211057-A1 MOLECULES HAVING COMBINABLE GROUPS NCAPH, NCL, NCAPD2 KMT2A 3310/4885RAB9A 2901/4885KDM4E 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.