SCHEMBL10018802

SCHEMBL10018802

C=CCOC(=C)c1cc(C(=O)OCC=C)c(C(=O)OCC=C)cc1C(=O)OCC=C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.59
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 2/20 0.51
TSHR P16473 2/20 0.51
SNCA P37840 1/20 0.40
RHOA P61586 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
APP P05067 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FGFR1 P11362 1/20 0.35
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL209680 0.90 CYP3A4 (0.70) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL27459185 0.83 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL982544 0.83 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL5831986 0.83 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL771170 0.83 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL12168706 0.82 CYP3A4 (0.56) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL12203027 0.82 CYP3A4 (0.56) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL4570283 0.81 CYP3A4 (0.59) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL30933424 0.79 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL29225979 0.79 CYP3A4 (0.61) CYP3A4ALDH1A1HSD17B10TSHRSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110065-B2 Heat-curable fluoropolyether adhesive composition and bonding method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-07 US disclosed
US-8110065-B2 Heat-curable fluoropolyether adhesive composition and bonding method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-07 US disclosed
US-20080289760-A1 HEAT-CURABLE FLUOROPOLYETHER ADHESIVE COMPOSITION AND BONDING METHOD SHIN-ETSU CHEMICAL CO, LTD. (JP) 2008-11-27 US disclosed
EP-1995289-A1 Heat-curable fluoropolyether adhesive composition and bonding method Shin-Etsu Chemical Co., Ltd. (JP) 2008-11-26 EP disclosed