Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368133 | 0.92 | CNR1 (0.39) | CNR1GAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL10019101 | 0.85 | TDP1 (0.36) | CNR1GAATDP1L3MBTL1KCNH2 | |
| SCHEMBL10019088 | 0.84 | PDK2 (0.31) | PDK2 | |
| SCHEMBL10019096 | 0.83 | SLC6A4 (0.33) | CNR1CYP2D6PDK2 | |
| SCHEMBL15870953 | 0.78 | CNR1 (0.37) | CNR1GAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL20407353 | 0.75 | CNR1 (0.34) | CNR1GAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL30655466 | 0.74 | APEX1 (0.48) | KDM4ETDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL83466 | 0.74 | APEX1 (0.48) | KDM4ETDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6060689 | 0.73 | APEX1 (0.47) | GAATDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14736023 | 0.73 | APEX1 (0.47) | GAATDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142855-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142855-A1 | MATERIALS FOR ELECTRONIC DEVICES | PEF1, PARG, EFNA1 | CNR1 4299/4885GAA 1967/4885KDM4E 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.