SCHEMBL10019686

SCHEMBL10019686

CCCCCc1ccc(OCc2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.38
CNR1 P21554 4/20 0.36
TSHR P16473 2/20 0.36
FFAR1 O14842 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35
TYR P14679 1/20 0.35
ALOX15 P16050 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020011 0.87 HRH3 (0.40) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL10019622 0.86 FFAR1 (0.35) FFAR1
SCHEMBL10019630 0.85 CACNA1C (0.36) FFAR1
SCHEMBL10019870 0.84 TYR (0.39) TSHRMEN1KMT2ATP53CYP3A4
SCHEMBL19622129 0.84 FFAR4 (0.37)
SCHEMBL10019632 0.84 CTSL (0.38) CNR2TSHRMEN1KMT2ATP53
SCHEMBL10020135 0.84 CTSL (0.38) CNR2TSHRMEN1KMT2ATP53
SCHEMBL19621962 0.84 CTSL (0.38) CNR2TSHRMEN1KMT2ATP53
SCHEMBL10020140 0.83 RXRG (0.36) CNR2TSHRMEN1KMT2ATP53
SCHEMBL10020036 0.82 S1PR1 (0.37) TSHRMEN1KMT2ATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed