SCHEMBL10019983

SCHEMBL10019983

CCCCCC1CCC(c2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019837 0.90 GAA (0.31) GAAMAPT
SCHEMBL12801462 0.87 CTSL (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL10019975 0.87
SCHEMBL7738846 0.86 MAPT (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL7738847 0.86 MAPT (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL9405715 0.86 MAPT (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL7738849 0.86 MAPT (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL9405720 0.86 MAPT (0.37) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL9405927 0.85 MAPT (0.39) GAAMAPTMEN1KMT2AOPRL1
SCHEMBL9406276 0.85 MAPT (0.39) GAAMAPTMEN1KMT2AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed