SCHEMBL10019986

SCHEMBL10019986

CCCc1ccc(-c2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(OCC)c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.36
GABRA1 P14867 4/20 0.36
GABRB2 P47870 4/20 0.36
FGFR2 P21802 2/20 0.36
FGFR1 P11362 1/20 0.36
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
MPL P40238 3/20 0.32
TP53 P04637 1/20 0.32
MDM2 Q00987 1/20 0.32
ALOX5 P09917 1/20 0.32
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
RARB P10826 1/20 0.30
CALM1 P0DP23 1/20 0.30
USP2 O75604 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019942 0.88 GABRA1 (0.34) FFAR4GABRA1GABRB2TP53CALM1
SCHEMBL10019960 0.87 GABRA1 (0.35) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL29873595 0.86 GABRA1 (0.42) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL3437380 0.86 GABRA1 (0.42) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL10019838 0.86 GABRA1 (0.36) GABRA1GABRB2CALM1
SCHEMBL10019978 0.85 GABRA1 (0.37) GABRA1GABRB2FGFR2FGFR1CALM1
SCHEMBL9563716 0.85 GABRA1 (0.41) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL21609905 0.85 GABRA1 (0.41) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL3437385 0.85 GABRA1 (0.41) FFAR4GABRA1GABRB2FGFR2FGFR1
SCHEMBL17946123 0.85 GABRA1 (0.41) FFAR4GABRA1GABRB2FGFR2FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed