SCHEMBL10020022

SCHEMBL10020022

C=CCCc1ccc(OCc2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
MAOB P27338 1/20 0.33
THRB P10828 1/20 0.32
FFAR4 Q5NUL3 10/20 0.32
FFAR1 O14842 4/20 0.32
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
CYSLTR2 Q9NS75 1/20 0.31
CYSLTR1 Q9Y271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020007 0.89 FFAR4 (0.32) MAOBFFAR4FFAR1
SCHEMBL10019622 0.88 FFAR1 (0.35) CTSLCTSSCTSKMAOBFFAR1
SCHEMBL10019842 0.87 CTSL (0.33) CTSLCTSSCTSKTHRB
SCHEMBL19622129 0.86 FFAR4 (0.37) MAOBFFAR4CYSLTR2CYSLTR1
SCHEMBL10019941 0.86 CTSL (0.35) CTSLCTSSCTSKFFAR4
SCHEMBL10020014 0.85 CTSL (0.33) CTSLCTSSCTSK
SCHEMBL10020011 0.85 HRH3 (0.40) FFAR4
SCHEMBL10019963 0.84 CTSL (0.31) CTSLCTSSCTSK
SCHEMBL10020141 0.83 CTSL (0.38) CTSLCTSSCTSK
SCHEMBL10019666 0.83 CTSL (0.38) CTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed