SCHEMBL10020151

SCHEMBL10020151

CCOc1ccc(C(F)(F)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 10/20 0.35
HCRTR2 O43614 10/20 0.35
PDK2 Q15119 2/20 0.34
LMNA P02545 2/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM1A O60341 2/20 0.31
CACNA1C Q13936 1/20 0.31
FGFR2 P21802 1/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019534 0.92 HCRTR1 (0.35) HCRTR1HCRTR2PDK2LMNAMAPT
SCHEMBL10019564 0.88 KDM1A (0.35) HCRTR1HCRTR2KDM1AFGFR2BRD4
SCHEMBL10020184 0.87 HCRTR1 (0.33) HCRTR1HCRTR2KDM1AFGFR2
SCHEMBL10019905 0.87 HCRTR1 (0.33) HCRTR1HCRTR2KDM1AFGFR2
SCHEMBL10019915 0.86 HCRTR1 (0.36) HCRTR1HCRTR2PDK2LMNAMAPT
SCHEMBL10020093 0.86 HCRTR1 (0.35) HCRTR1HCRTR2PDK2
SCHEMBL10020163 0.83 L3MBTL1 (0.40) HCRTR1HCRTR2PDK2LMNAMAPT
SCHEMBL10019531 0.83 HCRTR1 (0.33) HCRTR1HCRTR2BRD4
SCHEMBL15257977 0.82 PDK2 (0.36) PDK2LMNAMAPTATML3MBTL1
SCHEMBL10020094 0.81 HCRTR1 (0.33) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed