SCHEMBL10020495

SCHEMBL10020495

C/N=C\C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862556 1.00
SCHEMBL13335936 0.75
SCHEMBL18854459 0.72
SCHEMBL11605748 0.70 LMNA (0.34)
SCHEMBL10667700 0.70 LMNA (0.34)
SCHEMBL23488356 0.69
SCHEMBL14999446 0.69
SCHEMBL18843051 0.69
SCHEMBL14724318 0.69
SCHEMBL28269972 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2020-05-14 US disclosed
EP-3154997-B1 AURISTATIN DERIVATIVES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2020-02-19 EP disclosed
WO-2018069863-A1 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2018-04-19 WO disclosed
US-9809621-B2 Stable peptide-based PACE4 inhibitors SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2017-11-07 US disclosed
US-20170290927-A1 CHARGE-BALANCED IMAGING AGENTS BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2017-10-12 US disclosed
US-20170290928-A1 USE OF CHARGE-BALANCED IMAGING AGENTS FOR DETERMINING RENAL FUNCTION BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2017-10-12 US disclosed
US-9687567-B2 Charged-balanced imaging agents BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2017-06-27 US disclosed
EP-2136354-B1 Display device, liquid crystal display device and electronic device including the same SEMICONDUCTOR ENERGY LAB (JP) 2017-03-22 EP disclosed
WO-2015189791-A1 AURISTATIN DERIVATIVES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2015-12-17 WO disclosed
US-20150209451-A1 CHARGED-BALANCED IMAGING AGENTS BETH ISRAEL HOSPITAL (US) 2015-07-30 US disclosed
US-20150141324-A1 STABLE PEPTIDE-BASED FURIN INHIBITORS SOCPRA Sciences Sante et Humaines S.E.C. (CA) 2015-05-21 US disclosed
US-9023611-B2 Charged-balanced imaging agents BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2015-05-05 US disclosed
US-20140206622-A1 STABLE PEPTIDE-BASED PACE4 INHIBITORS SOCPRA Sciences Sante et Humaines S.E.C. (CA) 2014-07-24 US disclosed
US-20140200215-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. 2014-07-17 US disclosed
US-20120028291-A1 CHARGED-BALANCED IMAGING AGENTS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-02-02 US disclosed