SCHEMBL10021168

SCHEMBL10021168

COCc1ccc(C2CCCCC2)cc1F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 2/20 0.39
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 1/20 0.38
APP P05067 1/20 0.38
KDM5A P29375 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM5B Q9UGL1 1/20 0.38
DPP4 P27487 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
P2RX3 P56373 1/20 0.35
TLR7 Q9NYK1 5/20 0.35
BACE1 P56817 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
RORC P51449 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26179840 0.92 KDM5A (0.42) KDM5AKDM4CKDM5BTLR7RORC
SCHEMBL7031706 0.80 KDM5A (0.39) CYP3A4CYP2C9KDM5AKDM4CKDM5B
SCHEMBL8390750 0.80 KDM5A (0.39) CYP3A4CYP2C9KDM5AKDM4CKDM5B
SCHEMBL7032806 0.80 KDM5A (0.39) CYP2C9KDM5AKDM4CKDM5BTLR7
SCHEMBL7029268 0.80 CYP2C9 (0.43) CYP2C9KDM5AKDM4CKDM5BTLR7
SCHEMBL3902288 0.79 ACMSD (0.41) HTR1DCYP3A4CYP2C9APPDPP4
SCHEMBL3900939 0.79 HTR1D (0.41) HTR1DCYP3A4CYP2C9APPDPP4
SCHEMBL7732631 0.79 EPHX2 (0.35) HTR1DCYP3A4CYP2C9APPDPP4
SCHEMBL8385781 0.78 KDM5A (0.37) CYP3A4KDM5AKDM4CKDM5BTLR7
SCHEMBL8390577 0.78 KDM5A (0.35) KDM5AKDM4CKDM5BTLR7RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020643-A1 COMPOUND HAVING PROPYL ETHER AS BONDING GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC株式会社 (JP) 2012-02-16 WO disclosed