Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023456 | 0.90 | TDP1 (0.57) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL14192906 | 0.86 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL11941634 | 0.86 | LMNA (0.35) | LMNAL3MBTL1TDP1 | |
| SCHEMBL13841279 | 0.83 | — | — | |
| SCHEMBL12806699 | 0.77 | TDP1 (0.36) | TDP1 | |
| SCHEMBL14082117 | 0.77 | LMNA (0.36) | LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL13995222 | 0.76 | — | — | |
| SCHEMBL29429791 | 0.76 | LMNA (0.53) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL17993137 | 0.75 | TDP1 (0.32) | TDP1 | |
| SCHEMBL12514120 | 0.75 | TDP1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051423-A1 | ACTIVATABLE CYTOKINE POLYPEPTIDES AND METHODS OF USE THEREOF | WEREWOLF THERAPEUTICS, INC. | 2023-02-16 | — | — | US | disclosed |
| WO-2021078577-A1 | ANTI-REDEPOSITION DETERGENTS | HENKEL AG & CO. KGAA (DE) | 2021-04-29 | — | — | WO | disclosed |
| US-20120065088-A1 | SEQUENCE-SPECIFIC DETECTION OF NUCLEOTIDE SEQUENCES | GEORGETOWN UNIVERSITY (US) | 2012-03-15 | — | — | US | disclosed |