Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790022 | 0.92 | POLB (0.50) | POLB | |
| SCHEMBL10022245 | 0.91 | POLG (0.51) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL22327108 | 0.91 | POLG (0.51) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5664002 | 0.91 | POLG (0.51) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5664015 | 0.91 | POLG (0.51) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL24971027 | 0.85 | POLG (0.43) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL24971026 | 0.85 | POLG (0.43) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL21503943 | 0.84 | POLG (0.48) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL9840726 | 0.84 | DNMT1 (0.56) | — | |
| SCHEMBL8755221 | 0.84 | DNMT1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114403-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-04-27 | — | — | US | disclosed |
| US-20120021408-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2012-01-26 | — | — | US | disclosed |