Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755221 | 1.00 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL7222104 | 0.92 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL7222108 | 0.92 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL13823328 | 0.91 | DNMT1 (0.55) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL10015665 | 0.89 | DNMT1 (0.53) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL25492471 | 0.88 | DNMT1 (0.57) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL149389 | 0.88 | DNMT1 (0.57) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL442211 | 0.88 | DNMT1 (0.57) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL5983092 | 0.88 | DNMT1 (0.57) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL5983084 | 0.88 | DNMT1 (0.57) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280700-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-10-24 | — | — | US | disclosed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | disclosed |