SCHEMBL10023201

SCHEMBL10023201

c1ccc2cc(-c3ccc4cc(-c5ccc6cc(-c7ccc8c(c7)c7ccccc7n7c9ccccc9nc87)ccc6c5)ccc4c3)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.48
HPGD P15428 7/20 0.48
ALDH1A1 P00352 7/20 0.48
KMT2A Q03164 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 5/20 0.46
POLB P06746 3/20 0.46
LMNA P02545 3/20 0.46
HSD17B10 Q99714 2/20 0.46
TP53 P04637 2/20 0.46
MEN1 O00255 2/20 0.43
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10023378 1.00 KDM4E (0.48) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023564 1.00 KDM4E (0.48) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023530 0.99 KDM4E (0.47) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023223 0.97 KDM4E (0.46) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023573 0.95 KDM4E (0.44) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL22414084 0.94 HPGD (0.48) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023498 0.94 HPGD (0.48) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023220 0.94 KDM4E (0.43) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023565 0.94 HPGD (0.43) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL10023620 0.94 HPGD (0.43) KDM4EHPGDALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
US-9139562-B2 Nitrogen-containing heterocyclic compound and organic electronic device using the same LG CHEM, LTD. (KR) 2015-09-22 US disclosed
US-9139562-B2 Nitrogen-containing heterocyclic compound and organic electronic device using the same LG CHEM, LTD. (KR) 2015-09-22 US disclosed
US-8368062-B2 Nitrogen-containing heterocyclic compound and organic electronic device using the same LG CHEM, LTD. (KR) 2013-02-05 US disclosed
US-8368062-B2 Nitrogen-containing heterocyclic compound and organic electronic device using the same LG CHEM, LTD. (KR) 2013-02-05 US disclosed
WO-2012087067-A9 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 주식회사 엘지화학 (KR) 2012-09-07 WO disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
WO-2012087067-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 주식회사 엘지화학 (KR) 2012-06-28 WO disclosed
US-20120007069-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2012-01-12 US disclosed
US-20120007069-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2012-01-12 US disclosed
US-20110127513-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-06-02 US disclosed
US-20110127513-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007069-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, VDAC3 KDM4E 382/4885HPGD 854/4885ALDH1A1 2949/4885
US-20110127513-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, VDAC3 KDM4E 382/4885HPGD 854/4885ALDH1A1 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.