Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878973 | 0.74 | F2 (0.50) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL13710838 | 0.74 | — | — | |
| SCHEMBL10031622 | 0.74 | F2 (0.50) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL10023938 | 0.72 | F2 (0.48) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL12294332 | 0.72 | F2 (0.48) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL15825651 | 0.72 | F2 (0.48) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL18845608 | 0.70 | F2 (0.46) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL12600692 | 0.70 | F2 (0.46) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL12601406 | 0.70 | F2 (0.46) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL5075056 | 0.69 | F2 (0.44) | F2ELANECTSGCTRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142734-A1 | METHODS FOR TREATING TUMORS WITH THALIDOMIDE | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142734-A1 | METHODS FOR TREATING TUMORS WITH THALIDOMIDE | PGF, FLT4, HIF1AN | F2 4336/4885ELANE 890/4885CTSG 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.