PGF

Placenta growth factor · P49763 · PGF on Sugi Atlas →

280 patent compounds predicted against PGF, 226 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Geranin A (SCHEMBL1689479)	0.89	3/20
Geranin A (SCHEMBL29554993)	0.89	3/20
Geranin A (SCHEMBL31186795)	0.89	3/20
Geranin D (SCHEMBL30414509)	0.85	3/20
Selligueain A (SCHEMBL23699013)	0.79	3/20
Selligueain A (SCHEMBL29363150)	0.79	3/20
Selligueain A (SCHEMBL29511856)	0.79	3/20
SCHEMBL17548764	0.78	3/20
SCHEMBL31186789	0.72	3/20
SCHEMBL27426284	0.71	3/20
SCHEMBL27426382	0.71	3/20
SCHEMBL27426404	0.71	3/20
SCHEMBL31186800	0.68	3/20
SCHEMBL27426293	0.68	3/20
SCHEMBL30446332	0.67	3/20
SCHEMBL4742863	0.65	3/20
SCHEMBL4742865	0.65	3/20
SCHEMBL13452786	0.63	3/20
SCHEMBL31313363	0.63	3/20
Ourateaproanthocyanidin A (SCHEMBL4747623)	0.58	3/20

Clinical trials — most relevant to PGF by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession.	PHASE4	COMPLETED
LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention	PHASE4	RECRUITING
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders	PHASE3	UNKNOWN
Rosuvastatin in Order to Induce Preeclampsia Resolution in Severe PET up to 48 Hours Following Delivery	PHASE1/PHASE2	UNKNOWN
Trial of Zileuton CR in Children and Adults With Sickle Cell Disease	PHASE1	COMPLETED
The Relationship Between Second Trimester Placental Growth Factor Level and Fetal Growth Restriction	nan	UNKNOWN
PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)	nan	RECRUITING
Placental Growth Factor as a Predictor of Adverse Pregnancy Outcomes in Preeclamptic Women	nan	COMPLETED
Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure	nan	UNKNOWN
Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia	nan	COMPLETED
Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler	nan	COMPLETED
Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients	nan	COMPLETED
The Correlation Between Immunological Reaction of the Seminal Fluid in the Mother's Blood and Pregnancy Complications	nan	UNKNOWN
Fetal Growth and Pregnancy Complications Among Women With Heart Disease	nan	UNKNOWN
Identifying HDL Composition and Function in Preeclamptic and Normal Pregnancies	nan	COMPLETED
Precision Medicine for Prediction & Prevention of Early Pre-eclampsia	nan	UNKNOWN
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial	nan	UNKNOWN
Study of Pregnancy Regulation of Insulin and Glucose	nan	COMPLETED
EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction	nan	COMPLETED
The Preeclampsia Registry	nan	RECRUITING
Role of Placental Growth Factor (PlGF) in the Management of Non-Severe Preeclampsia	nan	UNKNOWN
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome	nan	UNKNOWN
Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy.	nan	COMPLETED
Placenta Imaging Project	nan	COMPLETED
Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone	nan	COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
C1q/TNF-related Protein 9 (CTRP 9) Level in Preeclamptic Obese and Non-obese Pregnancies	nan	COMPLETED
ANgiogenic Function at NOrmal TErm on Placenta	nan	RECRUITING
Danish Diabetes Birth Registry 2	nan	RECRUITING
Diagnostic Value of sFlt-1/PlGF Ratio for the Etiology of Intra Uterine Growth Restriction - ANGIOPAG	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a PGF binder may also engage these)

Protein	Name	Similarity
VEGFA	Vascular endothelial growth factor A, long form	0.995	landscape →
Q00731	—	0.994	Q00731 →
O76081	—	0.989	O76081 →
P49765	—	0.988	P49765 →
P49766	—	0.988	P49766 →
O55233	—	0.988	O55233 →
P0C6A0	—	0.987	P0C6A0 →
O95813	—	0.987	O95813 →
Q9Z0E3	—	0.986	Q9Z0E3 →
P79348	—	0.986	P79348 →
Q9H2A7	—	0.985	Q9H2A7 →
Q8N5Z5	—	0.985	Q8N5Z5 →
Q4R6Y5	—	0.985	Q4R6Y5 →
Q8WWF5	—	0.985	Q8WWF5 →
Q6AXU5	—	0.984	Q6AXU5 →
Q4TUC0	—	0.984	Q4TUC0 →
Q9XS49	—	0.984	Q9XS49 →
Q9GKE2	—	0.984	Q9GKE2 →
Q5DRQ5	—	0.984	Q5DRQ5 →
Q8BLR5	—	0.984	Q8BLR5 →
Q96PX9	—	0.984	Q96PX9 →
Q8WTX9	—	0.983	Q8WTX9 →
Q63572	—	0.983	Q63572 →
Q8TBE3	—	0.983	Q8TBE3 →
TESK1	Dual specificity testis-specific protein kinase 1	0.983	landscape →
Q76N89	—	0.983	Q76N89 →
O35485	—	0.983	O35485 →
P97946	—	0.983	P97946 →
Q8K4C5	—	0.983	Q8K4C5 →
Q5HZW5	—	0.982	Q5HZW5 →