Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRF1 | P14222 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12356031 | 0.96 | APP (0.67) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL10068367 | 0.89 | APP (0.58) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL30903822 | 0.88 | APP (0.94) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL30903823 | 0.88 | APP (0.94) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL30903820 | 0.88 | APP (0.94) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL5399485 | 0.88 | APP (0.94) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL7006689 | 0.86 | APP (0.91) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL2592315 | 0.85 | APP (1.00) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL14713496 | 0.85 | APP (1.00) | APPMAPTCYP2E1CYP3A4CYP2A6 | |
| SCHEMBL10055724 | 0.84 | APP (0.61) | APPMAPTGAAPTPN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673523-B2 | Image holding member for image forming apparatus, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-8664645-B2 | Organic electroluminescence element and display medium | FUJI XEROX CO., LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8475981-B2 | Image holding member for image forming apparatus, process cartridge, and image forming apparatus | FUJI XEROX, CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20120232242-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | FUJI XEROX CO., LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120187384-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| US-8207348-B2 | Thiazolothiazole compound and thiazolothiazole polymer | FUJI XEROX CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20120015290-A1 | IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20110207040-A1 | IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110086999-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | FUJI XEROX CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086999-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | ARL1, IRAK1, TYK2 | APP 1557/4885MAPT 477/4885CYP2E1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.