SCHEMBL10068367

SCHEMBL10068367

CCCc1ccc(N(c2ccc(-c3ccc(C=O)s3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.58
HSD17B1 P14061 6/20 0.40
HSD17B2 P37059 6/20 0.40
MAPT P10636 3/20 0.39
CYP2E1 P05181 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2B6 P20813 1/20 0.36
CYP2C19 P33261 1/20 0.36
PRF1 P14222 1/20 0.36
PGR P06401 1/20 0.35
GAA P10253 1/20 0.35
LTB4R2 Q9NPC1 1/20 0.34
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
GPX4 P36969 1/20 0.33
RAB9A P51151 1/20 0.33
PAX8 Q06710 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10023971 0.89 APP (0.73) APPMAPTCYP2E1CYP3A4CYP2A6
SCHEMBL12356031 0.86 APP (0.67) APPMAPTCYP2E1CYP3A4CYP2A6
SCHEMBL10083472 0.86 APP (0.50) APPHSD17B1HSD17B2MAPTLTB4R2
SCHEMBL11887488 0.82 HSD17B1 (0.39) APPHSD17B1HSD17B2MAPTPGR
SCHEMBL18286383 0.79 LTB4R2 (0.41) HSD17B1HSD17B2CYP2A6GAALTB4R2
SCHEMBL30862485 0.79 APP (0.70) APPHSD17B1HSD17B2MAPTCYP2E1
SCHEMBL29036191 0.79 APP (0.70) APPHSD17B1HSD17B2MAPTCYP2E1
SCHEMBL10068366 0.77 PSMB5 (0.44) MAPTGAALTB4R2NPC1RAB9A
SCHEMBL5399485 0.77 APP (0.94) APPMAPTCYP2E1CYP3A4CYP2A6
SCHEMBL30903823 0.77 APP (0.94) APPMAPTCYP2E1CYP3A4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673523-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-18 US disclosed
US-8664645-B2 Organic electroluminescence element and display medium FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8475981-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX, CO., LTD. (JP) 2013-07-02 US disclosed
US-20120187384-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY MEDIUM FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed
US-20120015290-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-01-19 US disclosed
US-20110207040-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-08-25 US disclosed