SCHEMBL10023973

SCHEMBL10023973

CCCc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.48
LIPG Q9Y5X9 1/20 0.48
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CHRM2 P08172 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
CHRM1 P11229 1/20 0.45
DRD1 P21728 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
ADRA1A P35348 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11887109 1.00 LPL (0.48) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL5688863 0.94 TAAR1 (0.44) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL15681404 0.94 TAAR1 (0.44) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL10068358 0.92 CNR2 (0.53) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL11887469 0.92 TAAR1 (0.47) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL14461270 0.92 TAAR1 (0.47) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL12922766 0.91 LPL (0.56) LPLLIPGALDH1A1L3MBTL1CYP3A4
SCHEMBL11887473 0.90 POLB (0.47) LPLLIPGALDH1A1L3MBTL1KDM4E
SCHEMBL11887134 0.90 TAAR1 (0.48) LPLLIPGALDH1A1KDM4EMAPT
SCHEMBL14004019 0.90 TAAR1 (0.48) LPLLIPGALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3249469-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD Tokyo Ohka Kogyo Co., Ltd. (JP) 2017-11-29 EP disclosed
US-9155159-B2 Light emitting device having quantum cut dots with a protecting material and prolonged drive lifetime and good color purity DAI NIPPON PRINTING CO., LTD. (JP) 2015-10-06 US disclosed
US-8673523-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-18 US disclosed
US-8664645-B2 Organic electroluminescence element and display medium FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8475981-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX, CO., LTD. (JP) 2013-07-02 US disclosed
US-20120232242-A1 THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER FUJI XEROX CO., LTD. (JP) 2012-09-13 US disclosed
US-20120187384-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY MEDIUM FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed
US-8207348-B2 Thiazolothiazole compound and thiazolothiazole polymer FUJI XEROX CO., LTD. (JP) 2012-06-26 US disclosed
CN-101470364-B Toner and method of manufacturing the same, two-component developer, developing apparatus, and image forming apparatus SHARP KK 2012-03-21 CN disclosed
US-20120015290-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-01-19 US disclosed
US-20110207040-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-08-25 US disclosed
US-20110086999-A1 THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER FUJI XEROX CO., LTD. (JP) 2011-04-14 US disclosed
EP-1821151-A1 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor Samsung Electronics Co., Ltd. (KR) 2007-08-22 EP disclosed
US-7255936-B2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-14 US disclosed
US-7255936-B2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086999-A1 THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER ARL1, IRAK1, TYK2 LPL 4371/4885LIPG 4876/4885ALDH1A1 193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.