Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | MIF | P14174 | 9/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | GAPDH | P04406 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300739 | 0.94 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2303012 | 0.91 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12386518 | 0.89 | NPC1 (0.78) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18509602 | 0.89 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL20275184 | 0.88 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL23052991 | 0.87 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21228893 | 0.87 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21884746 | 0.87 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18646593 | 0.86 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12386519 | 0.86 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022391-A2 | POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | VCL, LPXN, LCP1 | NPC1 4181/4885RAB9A 2121/4885MEN1 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.