SCHEMBL2303012

SCHEMBL2303012

C=C(C)C(=O)Oc1ccc2cc(-c3ccc(OC)cc3)c(=O)oc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.67
RAB9A P51151 6/20 0.67
RXFP1 Q9HBX9 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MIF P14174 1/20 0.65
SIRT3 Q9NTG7 1/20 0.65
ERAP1 Q9NZ08 1/20 0.65
KDM4E B2RXH2 1/20 0.62
GLA P06280 1/20 0.62
GAPDH P04406 1/20 0.55
HSD11B1 P28845 1/20 0.54
MAOB P27338 5/20 0.53
MAOA P21397 1/20 0.53
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
HPGD P15428 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
ACHE P22303 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2300739 0.94 NPC1 (0.66) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL10024034 0.91 NPC1 (0.62) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL803489 0.91 GAPDH (0.68) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL12386518 0.89 NPC1 (0.78) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL20288536 0.88 NPC1 (0.79) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL20275184 0.88 NPC1 (0.58) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL23052991 0.87 NPC1 (0.57) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL18509602 0.87 NPC1 (0.57) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL21228893 0.87 NPC1 (0.57) NPC1RAB9ARXFP1MEN1KMT2A
SCHEMBL21884746 0.87 NPC1 (0.57) NPC1RAB9ARXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
WO-2012022391-A2 POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-02-23 WO disclosed
WO-2011160765-A1 POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
WO-2011160764-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
WO-2011088882-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
WO-2011050893-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
WO-2011035842-A1 POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed
WO-2010049044-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY VCL, LPXN, LCP1 NPC1 4181/4885RAB9A 2121/4885RXFP1 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.