Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU1 | Q99519 | 14/20 | 0.45 |
| ▸ | NEU4 | Q8WWR8 | 6/20 | 0.45 |
| ▸ | NEU2 | Q9Y3R4 | 10/20 | 0.44 |
| ▸ | NEU3 | Q9UQ49 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23135371 | 0.85 | NEU1 (0.43) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL21695642 | 0.73 | NEU1 (0.46) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL23135372 | 0.73 | NEU1 (0.46) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL16544470 | 0.70 | NEU1 (0.57) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL22919828 | 0.70 | NEU2 (0.40) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL24437430 | 0.69 | NEU1 (0.42) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL17636054 | 0.68 | NEU1 (0.46) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL25060228 | 0.67 | NEU2 (0.38) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL23135680 | 0.67 | NEU1 (0.51) | NEU1NEU4NEU2NEU3 | |
| SCHEMBL22041103 | 0.65 | NEU1 (0.81) | NEU1NEU4NEU2NEU3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952183-B2 | Inhibitors of sialidase or sialidase-like enzymes | NATIONAL RESEARCH COUNCIL OF CANADA | 2015-02-10 | — | — | US | disclosed |
| US-20120046355-A1 | INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046355-A1 | INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES | NEU2, NEU1, NEU3 | NEU1 2/4885NEU4 7/4885NEU2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.