Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | HLCS | P50747 | 6/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024733 | 1.00 | TDP1 (0.49) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL27445341 | 0.84 | HLCS (0.58) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL27445991 | 0.83 | HLCS (0.59) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL20711427 | 0.83 | HLCS (0.59) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL27445635 | 0.81 | HLCS (0.61) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL27445364 | 0.80 | TDP1 (0.66) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL27448183 | 0.80 | TDP1 (0.70) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL23074635 | 0.78 | TDP1 (0.62) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL23074568 | 0.78 | TDP1 (0.61) | TDP1HLCSHPSECNR1MEN1 | |
| SCHEMBL7267179 | 0.78 | HLCS (0.71) | TDP1HLCSHPSECNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9080049-B2 | PH-sensitive graft copolymer, manufacturing method for same, and polymer micelles using method | Research & Business Foundation Sungkyunkwan University (KR) | 2015-07-14 | — | — | US | disclosed |
| US-20120027690-A1 | PH-SENSITIVE GRAFT COPOLYMER, MANUFACTURING METHOD FOR SAME, AND POLYMER MICELLES USING METHOD | Research & Business Foundation Sungkyunkwan University (KR) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027690-A1 | PH-SENSITIVE GRAFT COPOLYMER, MANUFACTURING METHOD FOR SAME, AND POLYMER MICELLES USING METHOD | MYADM, MYD88, PMM2 | TDP1 1422/4885HLCS 2833/4885HPSE 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.