Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922987 | 0.83 | MTNR1A (0.34) | CES1MTNR1AMTNR1B | |
| SCHEMBL10024811 | 0.74 | CES1 (0.37) | CES1MTNR1AMTNR1B | |
| SCHEMBL17173613 | 0.74 | CES1 (0.36) | CES1MTNR1AMTNR1B | |
| SCHEMBL17173624 | 0.74 | KMT2A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL17173552 | 0.71 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL17173549 | 0.71 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL14204843 | 0.70 | CES1 (0.40) | CES1MTNR1AMTNR1B | |
| SCHEMBL17173551 | 0.69 | CYP2C9 (0.41) | MTNR1AMTNR1B | |
| SCHEMBL18116178 | 0.68 | CYP2C9 (0.31) | MTNR1AMTNR1B | |
| SCHEMBL17173593 | 0.68 | CES1 (0.33) | CES1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180195003-A1 | PROCESS FOR THE STABILISATION OF LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180119010-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | US | disclosed |
| US-9347002-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-9212311-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2015-12-15 | — | — | US | disclosed |
| US-9090823-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9005721-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-9005720-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-8999459-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20140240653-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-28 | — | — | US | disclosed |
| US-20140152922-A1 | LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-06-05 | — | — | US | disclosed |
| US-20140028964-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20140022473-A1 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-20130306910-A1 | Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-8585925-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20130183460-A1 | LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20120162595-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120032112-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20110255048-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20100304049-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110255048-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, BPHL, LPXN | CES1 4416/4885MTNR1A 4478/4885MTNR1B 4664/4885 |
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, BPHL, LPXN | CES1 3952/4885MTNR1A 4190/4885MTNR1B 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.