Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597204 | 1.00 | — | — | |
| SCHEMBL7904557 | 0.97 | — | — | |
| SCHEMBL12961695 | 0.84 | — | — | |
| SCHEMBL13379346 | 0.84 | — | — | |
| SCHEMBL28905362 | 0.84 | TSHR (0.47) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL797619 | 0.83 | — | — | |
| SCHEMBL18574556 | 0.83 | — | — | |
| SCHEMBL8832872 | 0.79 | LMNA (0.31) | TSHRMEN1KMT2A | |
| SCHEMBL9179159 | 0.79 | LMNA (0.31) | TSHRMEN1KMT2A | |
| SCHEMBL2118202 | 0.79 | LMNA (0.31) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029520-A1 | Patient Selectable Joint Arthroplasty Devices and Surgical Tools | CONFORMIS, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110213368-A1 | Patient Selectable Joint Arthroplasty Devices and Surgical Tools | CONFORMIS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213374-A1 | Patient Selectable Joint Arthroplasty Devices and Surgical Tools | CONFORMIS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213431-A1 | Patient Selectable Joint Arthroplasty Devices and Surgical Tools | CONFORMIS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213373-A1 | Patient Selectable Joint Arthroplasty Devices and Surgical Tools | CONFORMIS, INC. (US) | 2011-09-01 | — | — | US | disclosed |