⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL11689760 | 0.78 | MEN1 (0.46) | — | |
| SCHEMBL3992204 | 0.72 | — | — | |
| SCHEMBL11386268 | 0.72 | MCL1 (0.56) | — | |
| SCHEMBL28171562 | 0.69 | — | — | |
| SCHEMBL788427 | 0.69 | — | — | |
| SCHEMBL30022145 | 0.69 | — | — | |
| SCHEMBL30536998 | 0.69 | — | — | |
| SCHEMBL16130 | 0.69 | — | — | |
| SCHEMBL27567423 | 0.69 | MCL1 (0.53) | — | |
| SCHEMBL6906172 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640921-B | Preparation method of tofacitinib citrate | 科兴生物制药股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-109810242-B | Epoxy resin for glass fiber reinforced plastic cabin cover of large power generation fan and preparation method thereof | 江苏华纳环保科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-111732595-A | Degatinib intermediate and preparation method thereof | 苏州明锐医药科技有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-111574540-A | Preparation method of degotatinib | 苏州明锐医药科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-111560021-A | Degaotinib intermediate and preparation method thereof | 苏州明锐医药科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-107602661-B | Preparation method of polaprezinc | 烟台万润药业有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-109053737-B | Preparation method of tofacitinib citrate compound | 山东罗欣药业集团恒欣药业有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-108948022-B | Synthesis method of tofacitinib | 山东罗欣药业集团恒欣药业有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-109810242-A | A kind of large size power generation fan glass fibre reinforced plastic nacelle cover epoxy resin and preparation method thereof | 江苏华纳环保科技有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-109053737-A | Preparation method of tofacitinib citrate compound | 山东罗欣药业集团恒欣药业有限公司 | 2018-12-21 | — | — | CN | claimed |
| US-7462663-B2 | Pressure-sensitive adhesive composition | LG CHEM, LTD. (KR) | 2008-12-09 | — | — | US | claimed |
| EP-1945731-A1 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION | LG Chem, Ltd. (KR) | 2008-07-23 | — | — | EP | claimed |
| EP-1937695-A1 | NOVEL ORGANIC SILANE COMPOUND | LG Chem, Ltd. (KR) | 2008-07-02 | — | — | EP | claimed |
| US-7262313-B2 | Organic silane compound | LG CHEM, LTD. (KR) | 2007-08-28 | — | — | US | claimed |
| US-20070093577-A1 | Pressure-sensitive adhesive composition | LG CHEM, LTD. (KR) | 2007-04-26 | — | — | US | claimed |
| US-20070093671-A1 | Organic silane compound | LG CHEM, LTD. (KR) | 2007-04-26 | — | — | US | claimed |
| WO-2007046646-A1 | NOVEL ORGANIC SILANE COMPOUND | LG CHEM, LTD. (KR) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046647-A1 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION | LG CHEM, LTD. (KR) | 2007-04-26 | — | — | WO | claimed |
| EP-0484223-B1 | 3-Cycloalkylpropanamides, their tautomers and salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | claimed |
| US-4139702-A | Process for preparing cephalosporines | DOBFAR S.P.A. (IT) | 1979-02-13 | — | — | US | claimed |