⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369766 | 0.71 | — | — | |
| SCHEMBL570228 | 0.69 | — | — | |
| SCHEMBL9949606 | 0.69 | — | — | |
| SCHEMBL1002595 | 0.69 | — | — | |
| SCHEMBL8588196 | 0.69 | — | — | |
| SCHEMBL3849153 | 0.67 | — | — | |
| SCHEMBL9719198 | 0.67 | — | — | |
| SCHEMBL11843414 | 0.67 | — | — | |
| SCHEMBL5909 | 0.67 | — | — | |
| SCHEMBL10675428 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197455-B1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME (US) | 2020-12-30 | — | — | EP | disclosed |
| EP-3197452-B1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME (US) | 2020-02-26 | — | — | EP | disclosed |
| US-10208060-B2 | Inhibitors of HIF prolyl hydroxylase | MERCK SHARP & DOHME CORP. (US) | 2019-02-19 | — | — | US | disclosed |
| US-10000501-B2 | Inhibitors of HIF prolyl hydroxylase | MERCK SHARP & DOHME CORP. (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170313718-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2017-11-02 | — | — | US | disclosed |
| US-20170240555-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2017-08-24 | — | — | US | disclosed |
| US-20170226120-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2017-08-10 | — | — | US | disclosed |
| EP-3197451-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | Merck Sharp & Dohme Corp. (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3197455-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | Merck Sharp & Dohme Corp. (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3197452-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | Merck Sharp & Dohme Corp. (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016049100-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016045128-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016049098-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016045126-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016045125-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| US-6730810-B2 | HOMOGENOUS MIXTURE COMPRISING ACID HALIDE WITH HYDROXY CARBOXYLIC ACIDS AND ANHYDRIDE; DISCOLORATION INHIBITION | HUNTSMAN PETROCHEMICAL CORPORATION | 2004-05-04 | — | — | US | disclosed |
| US-20030120089-A1 | Anhydride stabilization | HUNTSMAN PETROCHEMICAL CORPORATION | 2003-06-26 | — | — | US | disclosed |
| EP-0416547-B1 | Dithiocarbamate group-containing polyester | MITSUBISHI CHEM CORP (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5097007-A | Produces free radicals to initiate copolymerization with ethylenic monomers; photoresists, photocurable inks/paints | MISTUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0416547-A2 | Dithiocarbamate group-containing polyester | Mitsubishi Chemical Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |