SCHEMBL100262

SCHEMBL100262

CCCCCCCC(=O)SCCC[Si](OC)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 7/20 0.38
PPARD Q03181 7/20 0.38
PPARA Q07869 7/20 0.38
HDAC11 Q96DB2 5/20 0.38
TSHR P16473 4/20 0.38
PTPN1 P18031 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ALOX15 P16050 1/20 0.38
PDE4A P27815 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21049772 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL30205784 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL30205659 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL97747 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL21049771 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL30205650 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL96679 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL30205788 1.00 LMNA (0.45) LMNACES2CES1GPR84PPARG
SCHEMBL98569 0.98 LMNA (0.42) LMNACES2CES1GPR84PPARG
SCHEMBL30205662 0.95 LMNA (0.44) LMNACES2CES1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708547-A Metal-coated organic silicon resin microsphere and preparation method and application thereof 江苏涌新材料科技有限公司 2025-03-28 CN claimed
WO-2024010846-A2 CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME ZENITH PURIFICATION, LLC (US) 2024-01-11 WO claimed
US-20220363873-A1 SILANE COUPLING AGENT COMPOSITION COMPRISING SILANE COMPOUND AND PROTEIN MODIFYING AGENT, AND RUBBER COMPOSITION COMPRISING THE SAME ENEOS CORPORATION (JP) 2022-11-17 US claimed
EP-3981610-A1 SILANE COUPLING AGENT COMPOSITION CONTAINING SILANE COMPOUND AND PROTEIN DENATURING AGENT, AND RUBBER COMPOSITION CONTAINING SAID COMPOSITION ENEOS Corporation (JP) 2022-04-13 EP claimed
EP-2681272-B1 RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2015-07-08 EP claimed
EP-2426169-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2014-10-29 EP claimed
EP-2681272-A1 RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2014-01-08 EP claimed
US-8450408-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2013-05-28 US claimed
WO-2012118918-A1 RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-07 WO claimed
US-20120225231-A1 RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS, INC (US) 2012-09-06 US claimed
EP-2426169-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2012-03-07 EP claimed
US-20120046413-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2012-02-23 US claimed
US-20090143538-A1 Silane-Coupling-Agent-Treated Silica, Preparation Method Thereof, And Vibration-Damping And Vibration-Isolating Rubber Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2009-06-04 US claimed
US-7473724-B2 Preparation of silica reinforced polyisoprene-rich rubber composition and tire with component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-01-06 US claimed
US-20070244236-A1 Vibration-Damping And Vibration-Isolating Rubber Composition, Method Of Preparation Thereof, And Vibration-Damping And Vibration-Isolating Rubber Products DOW CORNING TORAY CO., LTD. (JP) 2007-10-18 US claimed
EP-1805254-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2007-07-11 EP claimed
EP-1781734-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP claimed
US-20060183831-A1 Preparation of silica reinforced polyisoprene-rich rubber composition and tire with component thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2006-08-17 US claimed
WO-2006016699-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO claimed
WO-2006016714-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO claimed