SCHEMBL10027430

SCHEMBL10027430

CC1COC(C2CCC(c3cc(F)c(C(F)(F)Oc4cc(F)c(F)c(F)c4)c(F)c3)OC2)OC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13164842 0.90
SCHEMBL16790904 0.90
SCHEMBL13419356 0.88
SCHEMBL13433623 0.86
SCHEMBL12357151 0.86
SCHEMBL16546287 0.85
SCHEMBL16546322 0.85
SCHEMBL13401014 0.83
SCHEMBL10018750 0.83
SCHEMBL10259408 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323209-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-11447701-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2022-09-20 US disclosed
US-11359142-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2022-06-14 US disclosed
US-11326102-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2022-05-10 US disclosed
US-11060029-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
US-20210207029-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2021-07-08 US disclosed
US-20210189241-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2021-06-24 US disclosed
US-10883047-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-01-05 US disclosed
US-20200385636-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-12-10 US disclosed
US-10774061-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2020-09-15 US disclosed
US-20160298033-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
US-20160298033-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
US-8585925-B2 Liquid-crystalline medium and liquid-crystal display MERCK PATENT GMBH (DE) 2013-11-19 US disclosed
EP-2393902-B1 LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
US-20120032112-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-02-09 US disclosed
US-7790247-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2010-09-07 US disclosed
US-20090309065-A1 LIQUID-CRYSTALLINE MEDIUM WITTEK MICHAEL 2009-12-17 US disclosed
US-7622165-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2009-11-24 US disclosed
EP-2100944-A1 Liquid crystal medium and liquid crystal display MERCK PATENT GmbH (DE) 2009-09-16 EP disclosed
US-20080085380-A1 Electrooptical apparatus; have a very low threshold voltage at the same time as high dielectric anisotropy, a high clearing point, large specific resistance and low birefringence MERCK PATENT GMBH 2008-04-10 US disclosed