SCHEMBL10027587

SCHEMBL10027587

c1ccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5cccc(-c6cccc(-n7c8ccccc8c8ccccc87)c6)n5)c4cc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
KMT2A Q03164 4/20 0.35
IL1R1 P14778 1/20 0.35
MEN1 O00255 3/20 0.34
RAB9A P51151 1/20 0.34
HTT P42858 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
GAA P10253 2/20 0.34
RXFP1 Q9HBX9 1/20 0.33
PDE10A Q9Y233 1/20 0.33
CNR1 P21554 1/20 0.33
COMT P21964 1/20 0.32
PTGER4 P35408 1/20 0.31
MDM2 Q00987 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12691265 0.97 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10060917 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10027583 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10060778 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17248215 0.94 ATM (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18833213 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10061162 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17248220 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10061784 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10027567 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed