SCHEMBL10027602

SCHEMBL10027602

c1ccc(-n2c3ccccc3c3nc4c5ccccc5n(-c5ccccc5)c4cc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.63
KDM4E B2RXH2 2/20 0.63
ATM Q13315 1/20 0.63
MAPK1 P28482 3/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 4/20 0.40
TSHR P16473 2/20 0.40
MAPK8 P45983 2/20 0.39
IL1R1 P14778 1/20 0.39
MEN1 O00255 2/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PGR P06401 1/20 0.39
LMNA P02545 1/20 0.39
MAPK9 P45984 1/20 0.38
MAPT P10636 1/20 0.38
KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17248323 0.92 KDM4E (0.58) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17251033 0.89 L3MBTL1 (0.59) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10206205 0.87 KDM4E (0.49) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10206162 0.87 KDM4E (0.49) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17248176 0.86 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL15490791 0.85 L3MBTL1 (0.46) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10027580 0.84 L3MBTL1 (0.58) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17251017 0.82 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17251031 0.81 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17051458 0.79 KDM4E (0.55) L3MBTL1KDM4EATMMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416627-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2019-01-02 EP disclosed
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
EP-2492987-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-08-29 EP disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 US disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 US disclosed
EP-2416627-A1 ORGANIC ELECTROLUMINESCENT DEVICE Nippon Steel Chemical Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed