⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283370 | 0.83 | — | — | |
| SCHEMBL28287867 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL642464 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL10537224 | 0.76 | — | — | |
| SCHEMBL6630544 | 0.76 | — | — | |
| SCHEMBL6912305 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL380063 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL6915728 | 0.74 | — | — | |
| SCHEMBL6912738 | 0.74 | — | — | |
| SCHEMBL9615912 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741951-B2 | Non-steroidal compounds for androgen receptor modulation | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-06-03 | — | — | US | disclosed |
| US-8741951-B2 | Non-steroidal compounds for androgen receptor modulation | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-06-03 | — | — | US | disclosed |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-02-16 | — | — | US | disclosed |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-02-16 | — | — | US | disclosed |