Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL31210069 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL31357301 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL138674 | 0.96 | CA1 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL3283210 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL8140299 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL7042513 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL10488816 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL18197505 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 | |
| Palmitic Acid SCHEMBL8511539 | 0.96 | CA1 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL28961972 | 0.96 | FABP3 (0.62) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305380-A1 | Methods for generating and recycling metal halide catalyst compositions for aromatic ring halogenation | SABIC Innovative Plastics IP B.V. (NL) | 2011-04-06 | — | — | EP | claimed |
| US-7863209-B2 | Methods for recycling catalyst compositions for aromatic ring halogenation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-01-04 | — | — | US | claimed |
| US-7763760-B2 | Catalyst composition and method for halogenating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-07-27 | — | — | US | claimed |
| JP-2008503462-A | — | — | 2008-02-07 | — | — | JP | claimed |
| JP-2008503461-A | — | — | 2008-02-07 | — | — | JP | claimed |
| EP-1778398-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1758679-A2 | METHODS FOR GENERATING AND RECYCLING METAL HALIDE CATALYST COMPOSITIONS FOR AROMATIC RING HALOGENATION | GENERAL ELECTRIC COMPANY (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006009661-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | claimed |
| WO-2006009662-A2 | METHODS FOR GENERATING AND RECYCLING METAL HALIDE CATALYST COMPOSITIONS FOR AROMATIC RING ALOGENATION | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | claimed |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | claimed |
| US-20050283034-A1 | Methods for recycling catalyst compositions for aromatic ring halogenation | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | claimed |
| EP-2305380-A1 | Methods for generating and recycling metal halide catalyst compositions for aromatic ring halogenation | SABIC Innovative Plastics IP B.V. (NL) | 2011-04-06 | — | — | EP | disclosed |
| US-7863209-B2 | Methods for recycling catalyst compositions for aromatic ring halogenation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-01-04 | — | — | US | disclosed |
| US-7763760-B2 | Catalyst composition and method for halogenating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-07-27 | — | — | US | disclosed |
| EP-1778398-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1758679-A2 | METHODS FOR GENERATING AND RECYCLING METAL HALIDE CATALYST COMPOSITIONS FOR AROMATIC RING HALOGENATION | GENERAL ELECTRIC COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006009662-A2 | METHODS FOR GENERATING AND RECYCLING METAL HALIDE CATALYST COMPOSITIONS FOR AROMATIC RING ALOGENATION | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2006009661-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | disclosed |
| US-20050283034-A1 | Methods for recycling catalyst compositions for aromatic ring halogenation | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050283034-A1 | Methods for recycling catalyst compositions for aromatic ring halogenation | PRKACG, HCN4, CLIC4 | FABP3 4440/4885CA1 1141/4885CES2 2366/4885 |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | AOC2, TYR, PRKX | FABP3 4768/4885CA1 198/4885CES2 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.