AOC2

Amine oxidase [copper-containing] 2 · O75106 · AOC2 on Sugi Atlas →

7,894 patent compounds predicted against AOC2, 3,963 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1295412	0.47	7/20
SCHEMBL1295416	0.47	7/20
SCHEMBL1295883	0.47	7/20
SCHEMBL1295255	0.67	6/20
SCHEMBL1295256	0.67	6/20
SCHEMBL1295390	0.67	6/20
Hydrochloric Acid (SCHEMBL2946124)	0.52	6/20
Hydrochloric Acid (SCHEMBL2946126)	0.52	6/20
Hydrochloric Acid (SCHEMBL2946127)	0.52	6/20
Mofegiline (SCHEMBL147813)	1.00	5/20
SCHEMBL1294789	1.00	5/20
SCHEMBL1294791	1.00	5/20
SCHEMBL1294793	1.00	5/20
Mofegiline (SCHEMBL1295041)	1.00	5/20
Mofegiline (SCHEMBL1295043)	1.00	5/20
Mofegiline (SCHEMBL125286)	0.96	5/20
Mofegiline (SCHEMBL343685)	0.96	5/20
Mofegiline (SCHEMBL343686)	0.96	5/20
SCHEMBL1294846	0.73	5/20
SCHEMBL1294847	0.73	5/20

Clinical trials — most relevant to AOC2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Pharmacogenomic Evaluation of Antihypertensive Responses	PHASE4	COMPLETED
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.	PHASE1/PHASE2	COMPLETED
Safety Study of High Doses of Zinc in ALS Patients	PHASE1/PHASE2	COMPLETED
Copper Histidine Therapy for Menkes Diseases	PHASE1/PHASE2	COMPLETED
Inosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical Trial	PHASE2	COMPLETED
Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study	PHASE1	WITHDRAWN
Prevalence of DAO (diamino Oxidase) Deficiency in Newborns	nan	COMPLETED
Personalizing Preterm Neonatal Transfusions With Fetal Hemoglobin-Enriched Cord Blood	nan	NOT_YET_RECRUITING
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Clinical, Cellular, and Molecular Investigation Into Oculocutaneous Albinism	nan	COMPLETED
Molecular Epidemiology of Parkinson's Disease	nan	COMPLETED
Effect of Oral L-arginine 3.32 g a Day on Oxidative Stress Influencing Beta Cell Function and Insulin Resistance.	nan	NOT_YET_RECRUITING
Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure	nan	UNKNOWN
The Association Between Executive Functions and Candidate Genes of Dopaminergic and Noradrenergic Systems in Attention Deficit Hyperactivity Disorder (ADHD)	nan	COMPLETED
Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC	nan	COMPLETED
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China	nan	COMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia	nan	UNKNOWN
Parkinson's Diseases Susceptibility Genes and Pesticides	nan	COMPLETED
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
Genetics of Obsessive-Compulsive Disorder	nan	COMPLETED
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)	nan	COMPLETED
Prevalence of High Plasmatic 3OMethyldopa Level in a Specific Population of Patients With a Symptomatology Compatible With AADC Deficiency	nan	UNKNOWN
Vitamin C Level Effect in Orthognathic Surgery	nan	COMPLETED
Covid-19: Possible Role of Neutrophil Extracellular Traps	nan	UNKNOWN
Palatability of Antioxidant Biscuits	nan	WITHDRAWN
Reactive Oxygen Species Following Aortic Valve Replacement	nan	COMPLETED
Parkinson's Families Project	nan	RECRUITING
Genetic DAO Deficiency and Lower Urinary Tract Symptoms	nan	COMPLETED
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Treating Oxidative Stress and the Metabolic Pathology of Autism	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a AOC2 binder may also engage these)

Protein	Name	Similarity
AOC3	Amine oxidase [copper-containing] 3	1.000	landscape →
O70423	—	1.000	O70423 →
AOC1	Diamine oxidase [copper-containing]	1.000	landscape →
Q812C9	—	1.000	Q812C9 →
O08590	—	0.997	O08590 →
Q5R9I0	—	0.996	Q5R9I0 →
Q9TRC7	—	0.996	Q9TRC7 →
P36633	—	0.996	P36633 →
Q9TTK6	—	0.995	Q9TTK6 →
O46406	—	0.994	O46406 →
Q8JZQ5	—	0.993	Q8JZQ5 →
Q29437	—	0.990	Q29437 →
Q2KHV9	—	0.976	Q2KHV9 →
Q0V8J4	—	0.975	Q0V8J4 →
Q09200	—	0.975	Q09200 →
Q9UGT4	—	0.974	Q9UGT4 →
Q9JHA8	—	0.974	Q9JHA8 →
Q6MG64	—	0.974	Q6MG64 →
Q13724	—	0.973	Q13724 →
Q9DBX3	—	0.973	Q9DBX3 →
Q9Y334	—	0.972	Q9Y334 →
Q5RDJ3	—	0.972	Q5RDJ3 →
P82350	—	0.972	P82350 →
Q8QZW3	—	0.972	Q8QZW3 →
Q16586	—	0.972	Q16586 →
Q5T197	—	0.971	Q5T197 →
Q3UH93	—	0.971	Q3UH93 →
Q7ZV46	—	0.971	Q7ZV46 →
O54782	—	0.971	O54782 →
Q8IYS2	—	0.970	Q8IYS2 →