SCHEMBL10029475

SCHEMBL10029475

CCc1ccccc1C(C)(C)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 1/20 0.35
ATM Q13315 1/20 0.35
MGLL Q99685 1/20 0.34
HSP90AA1 P07900 1/20 0.34
IDO1 P14902 2/20 0.33
CTSB P07858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLQ O75417 1/20 0.33
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13462919 0.82 GABRA1 (0.40) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL29947075 0.79 MAPK1 (0.42) GABRA1GABRB2NPSR1HSP90AA1ALDH1A1
SCHEMBL6900861 0.79 MAPK1 (0.42) GABRA1GABRB2NPSR1HSP90AA1ALDH1A1
SCHEMBL984512 0.79 GABRA1 (0.42) GABRA1GABRB2MAPTALDH1A1SMN1; SMN2
SCHEMBL1521882 0.78 GABRA1 (0.48) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL16105766 0.78 GABRA1 (0.48) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL984514 0.77 GABRA1 (0.41) GABRA1GABRB2MAPTATMALDH1A1
SCHEMBL19025158 0.76 IDO1 (0.36) IDO1ALDH1A1POLQ
SCHEMBL18243210 0.76 GABRA1 (0.46) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL12631962 0.74 GABRA1 (0.44) GABRA1GABRB2MAPTNPSR1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2781556-B1 Method of colouring and lightening keratin materials in the presence of a reducing agent comprising a fluorescent disulphide dye L'ORÉAL (FR) 2017-03-01 EP disclosed
US-8992801-B2 Electroactive material, and use thereof in anodes for lithium-ion cells BASF SE (DE) 2015-03-31 US disclosed
US-20120032109-A1 ELECTROACTIVE MATERIAL, AND USE THEREOF IN ANODES FOR LITHIUM-ION CELLS BASF SE (DE) 2012-02-09 US disclosed