SCHEMBL10030764

SCHEMBL10030764

COC(=O)C(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CYP1A2 P05177 1/20 0.53
CYP2A6 P11509 1/20 0.53
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HSD17B10 Q99714 1/20 0.50
FAAH O00519 1/20 0.49
EPHX1 P07099 1/20 0.49
PPARG P37231 3/20 0.47
RAB9A P51151 3/20 0.47
PPARA Q07869 2/20 0.47
PTPN7 P35236 1/20 0.47
NPC1 O15118 2/20 0.46
CASP3 P42574 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
MMP1 P03956 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030775 0.92 KDM4E (0.46) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL21881869 0.90 KMT2A (0.66) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL28711125 0.87 KDM4E (0.55) KMT2AMEN1MAPTCYP1A2CYP2A6
SCHEMBL14390574 0.84 CYP1A2 (0.53) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL14514195 0.83 KMT2A (0.58) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL36603 0.80 ELANE (0.58) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL29801955 0.80 ELANE (0.58) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL31476932 0.80 ELANE (0.58) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL19333554 0.79 KMT2A (0.53) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL28582715 0.79 KMT2A (0.53) KMT2AMEN1MAPTTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME OTC, ODC1, OXGR1 KMT2A 1371/4885MEN1 4576/4885MAPT 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.