SCHEMBL10030775

SCHEMBL10030775

COC(=O)C(=O)Oc1ccc2cc(OC(=O)C(=O)OC)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
NCEH1 Q6PIU2 1/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
HGFAC Q04756 1/20 0.42
PTGS1 P23219 3/20 0.42
AKR1C3 P42330 3/20 0.42
AKR1C2 P52895 3/20 0.42
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTGS2 P35354 3/20 0.41
CYP1A2 P05177 2/20 0.41
CDC42 P60953 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28711125 0.94 KDM4E (0.55) KDM4EMAPTKMT2AMEN1PTGS1
SCHEMBL10030764 0.92 KMT2A (0.56) KDM4EMAPTKMT2AMEN1TDP1
SCHEMBL28707047 0.85 L3MBTL1 (0.59) KDM4EMAPTKMT2AMEN1TDP1
SCHEMBL28707622 0.82 L3MBTL1 (0.68) KDM4EMAPTKMT2AMEN1TDP1
SCHEMBL21881869 0.80 KMT2A (0.66) KDM4EMAPTKMT2AMEN1TDP1
SCHEMBL2944091 0.80 KDM4E (0.47) KDM4ENCEH1MAPTKMT2AMEN1
SCHEMBL7065322 0.80 CA1 (0.54) MAPTKMT2ACA12CA9LMNA
SCHEMBL17355806 0.79 SMN1; SMN2 (0.54) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL7063122 0.78 LMNA (0.59) KDM4EMAPTKMT2ATDP1CA9
SCHEMBL17355780 0.77 RAB9A (0.41) MAPTKMT2ATDP1L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed
WO-2007124073-A2 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME OTC, ODC1, OXGR1 KDM4E 104/4885NCEH1 1908/4885MAPT 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.