Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116361 | 0.92 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL33527815 | 0.88 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18116369 | 0.88 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13383386 | 0.83 | TSHR (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL700993 | 0.80 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2456569 | 0.79 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29466118 | 0.76 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2606274 | 0.76 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14173057 | 0.76 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28584448 | 0.75 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883873-B2 | Polymerizable polymeric photoinitiators and radiation curable compositions | AGFA GRAPHICS NV (BE) | 2014-11-11 | — | — | US | disclosed |
| US-8883873-B2 | Polymerizable polymeric photoinitiators and radiation curable compositions | AGFA GRAPHICS NV (BE) | 2014-11-11 | — | — | US | disclosed |
| US-8492452-B2 | Polymerizable photoinitiators and radiation curable compositions | AGFA GRAPHICS NV (BE) | 2013-07-23 | — | — | US | disclosed |
| US-8492452-B2 | Polymerizable photoinitiators and radiation curable compositions | AGFA GRAPHICS NV (BE) | 2013-07-23 | — | — | US | disclosed |
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | disclosed |
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2011-09-15 | — | — | US | disclosed |
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2011-09-15 | — | — | US | disclosed |
| WO-2010133381-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010069758-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-06-24 | — | — | WO | disclosed |
| EP-2199273-A1 | Polymerizable photoinitiators and radiation curable compositions | AGFA Graphics NV (BE) | 2010-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224324-A1 | POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | WEE1, ZYX, MTR | TSHR 3503/4885ALDH1A1 632/4885TP53 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.