Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 6/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031316 | 0.88 | SLC5A1 (0.37) | SLC5A1SLC5A2KCNH2TMEM97SIGMAR1 | |
| SCHEMBL10064335 | 0.86 | CHRM4 (0.38) | CYP17A1CHRM4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14285952 | 0.80 | SLC5A1 (0.43) | SLC5A1SLC5A2P2RX3 | |
| SCHEMBL14285953 | 0.76 | SLC5A2 (0.41) | SLC5A1SLC5A2P2RX3 | |
| SCHEMBL10031310 | 0.76 | SLC5A1 (0.56) | SMN1; SMN2SLC5A1SLC5A2ALDH1A1L3MBTL1 | |
| SCHEMBL2044343 | 0.75 | SLC5A2 (0.69) | SLC5A1SLC5A2 | |
| SCHEMBL3772131 | 0.75 | SLC5A2 (0.69) | SLC5A1SLC5A2 | |
| SCHEMBL13446339 | 0.75 | SLC5A2 (0.69) | SLC5A1SLC5A2 | |
| SCHEMBL3772126 | 0.74 | SLC5A2 (0.47) | SLC5A1SLC5A2 | |
| SCHEMBL10064334 | 0.73 | PDE1A (0.38) | SMN1; SMN2NPC1RAB9ASLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053330-A1 | Chemical Process | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053330-A1 | Chemical Process | SLC5A2, SLC5A1, UGGT1 | CYP17A1 1093/4885CHRM4 3922/4885SMN1; SMN2 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.