Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369692 | 1.00 | EPHX2 (0.45) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16138612 | 0.87 | EPHX2 (0.45) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL567073 | 0.86 | EPHX2 (0.44) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL567075 | 0.86 | EPHX2 (0.44) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL567831 | 0.86 | EPHX2 (0.44) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL567370 | 0.86 | EPHX2 (0.44) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL567833 | 0.86 | EPHX2 (0.44) | EPHX2MIFMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10031344 | 0.81 | NOTUM (0.46) | MIFKDM4EMEN1KMT2AMAOB | |
| SCHEMBL567134 | 0.81 | NOTUM (0.46) | MIFKDM4EMEN1KMT2AMAOB | |
| SCHEMBL567133 | 0.81 | NOTUM (0.46) | MIFKDM4EMEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296285-A1 | PREPARATION AND APPLICATION OF THE NEW ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | YANG GENGLIANG (CN) | 2014-10-02 | — | — | US | disclosed |
| US-20140296285-A1 | PREPARATION AND APPLICATION OF THE NEW ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | YANG GENGLIANG (CN) | 2014-10-02 | — | — | US | disclosed |
| EP-2423213-A1 | PREPARATION AND USE OF NOVEL ANTIBIOTIC, ANTICANCER COMPOUNDS AND DERIVATIVES THEREOF | Yang, Gengliang (CN) | 2012-02-29 | — | — | EP | disclosed |
| US-20120035206-A1 | PREPARATION AND APPLICATION OF NOVEL ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | YANG, Gengliang (CN) | 2012-02-09 | — | — | US | disclosed |
| US-20120035206-A1 | PREPARATION AND APPLICATION OF NOVEL ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | YANG, Gengliang (CN) | 2012-02-09 | — | — | US | disclosed |
| EP-0196803-B1 | BENZENE-FUSED HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4692444-A | DIURETICS, VASODILATORS, HYPOTENSIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-08 | — | — | US | disclosed |
| EP-0196803-A2 | Benzene-fused heterocyclic compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035206-A1 | PREPARATION AND APPLICATION OF NOVEL ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | MRPL21, NRDC, SOST | EPHX2 3435/4885MIF 803/4885MAPT 4037/4885 |
| US-20140296285-A1 | PREPARATION AND APPLICATION OF THE NEW ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES | MRPL21, MCL1, MYC | EPHX2 4756/4885MIF 300/4885MAPT 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.