SCHEMBL10031390

SCHEMBL10031390

COc1ccc2cc3sc4c5cc6cc(OC)ccc6cc5sc4c3cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 1/20 0.48
BACE1 P56817 1/20 0.47
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
PDE3B Q13370 2/20 0.42
PDE3A Q14432 2/20 0.42
RAB9A P51151 2/20 0.42
CA2 P00918 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 2/20 0.41
GSTP1 P09211 1/20 0.41
PDK1 Q15118 1/20 0.40
PRNP P04156 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
PPARG P37231 1/20 0.40
HTT P42858 1/20 0.40
MAPK10 P53779 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10031370 1.00 CYP1A2 (0.48) CYP1A2CYP2A6BACE1HSD17B1HSD17B2
SCHEMBL20111029 0.80 KDM4E (0.40) RAB9AKDM4EMAPK1PPARGNCF1
SCHEMBL10031374 0.80 HTT (0.51) CYP1A2BACE1PDE3BPDE3ACYP3A4
SCHEMBL20932902 0.80 MAPT (0.56) CYP1A2CYP2A6BACE1RAB9ACYP3A4
SCHEMBL18252673 0.79 HTT (0.50) CYP1A2PDE3BPDE3ACYP3A4CYP2C19
SCHEMBL13923222 0.79 PDE4A (0.41) CYP3A4KDM4ETSHRALDH1A1MAPT
SCHEMBL20111032 0.78 CA2 (0.49) CA2CYP3A4KDM4EALDH1A1MAPT
SCHEMBL10031363 0.77 CYP2A6 (0.52) CYP1A2CYP2A6BACE1RAB9AKDM4E
SCHEMBL4730464 0.77 KDM4E (0.53) CYP1A2BACE1PDE3BPDE3ARAB9A
SCHEMBL17037120 0.77 CYP2A6 (0.52) CYP1A2CYP2A6BACE1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9680112-B2 Semiconductor composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-13 US disclosed
US-9203038-B2 Electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-01 US disclosed
US-20150123041-A1 SEMICONDUCTOR COMPOSITION SAMSUNG ELECTRONICS CO LTD (KR) 2015-05-07 US disclosed
US-20150053961-A1 ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2015-02-26 US disclosed
US-8963131-B2 Electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-24 US disclosed
US-8945425-B2 Semiconductor composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-03 US disclosed
US-8643001-B2 Semiconductor composition SAMSUNG ELECTRONICS CO. LTD. (KR) 2014-02-04 US disclosed
US-20120313081-A1 ELECTRONIC DEVICE XEROX CORPORATION (US) 2012-12-13 US disclosed
US-20120261648-A1 SEMICONDUCTOR COMPOSITION XEROX CORPORATION (US) 2012-10-18 US disclosed
US-20120161110-A1 SEMICONDUCTOR COMPOSITION XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20090043113-A1 Heteroacene compound, organic thin film including a heteroacene compound and electronic device including an organic thin film SAMSUNG ELECTRONICS CO., LTD. 2009-02-12 US disclosed
US-20090043113-A1 Heteroacene compound, organic thin film including a heteroacene compound and electronic device including an organic thin film SAMSUNG ELECTRONICS CO., LTD. 2009-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043113-A1 Heteroacene compound, organic thin film including a heteroacene compound and electronic device including an organic thin film EED, TEAD2, TEAD1 CYP1A2 847/4885CYP2A6 1708/4885BACE1 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.