SCHEMBL1003152

SCHEMBL1003152

CCCCCCCCCCCCCC(CCC)(c1cc(C(C)(C)C)c(OP(O)O)cc1C)c1cc(C(C)(C)C)c(OP(O)O)cc1C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.38
CNR2 P34972 4/20 0.33
CNR1 P21554 3/20 0.33
ESR2 Q92731 2/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
AR P10275 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ACAT1 P24752 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7748636 0.81 ALOX15 (0.46) ESR1CNR2CNR1ESR2AR
SCHEMBL5086030 0.79 ALOX15 (0.49) ESR1CNR2CNR1ESR2AR
SCHEMBL1160157 0.78 CNR2 (0.35) CNR2CNR1THRATHRB
SCHEMBL226008 0.78
SCHEMBL29871222 0.78 ALOX15 (0.36) KDM4ETP53CYP3A4MAPTALOX15
SCHEMBL11129316 0.78 ALOX15 (0.36) KDM4ETP53CYP3A4MAPTALOX15
SCHEMBL29660546 0.78 TP53 (0.49) THRATHRBTP53ALOX15
SCHEMBL9579467 0.77 TP53 (0.34) ESR1CNR2CNR1TP53CYP3A4
SCHEMBL1159820 0.75 CNR2 (0.35) CNR2CNR1
SCHEMBL919019 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2270101-B1 SYNTHETIC RESIN COMPOSITION, AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL COMPRISING THE SAME ADEKA CORP (JP) 2016-01-13 EP disclosed
US-8785527-B2 Synthetic resin composition and automotive interior/exterior material comprising the same ADEKA CORPORATION (JP) 2014-07-22 US disclosed
US-20110028611-A1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL COMPRISING THE SAME ADEKA CORPORATION (JP) 2011-02-03 US disclosed
EP-2270101-A1 SYNTHETIC RESIN COMPOSITION, AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL COMPRISING THE SAME Adeka Corporation (JP) 2011-01-05 EP disclosed
EP-1743928-A1 SEALING MATERIAL COMPOSITION KANEKA CORPORATION (JP) 2007-01-17 EP disclosed
US-5395869-A Thermally stabilized thermoplastic cycloolefin in resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-03-07 US disclosed