Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.60 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.60 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333758 | 1.00 | MAPK1 (0.75) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL10333760 | 1.00 | MAPK1 (0.75) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL10334235 | 1.00 | MAPK1 (0.75) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL16392632 | 0.99 | MAPK1 (0.73) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL16393106 | 0.99 | MAPK1 (0.73) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL14444732 | 0.96 | MAPK1 (0.72) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL10333912 | 0.90 | LGALS3 (0.68) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL10333913 | 0.90 | LGALS3 (0.68) | MAPK1LGALS8LGALS3LGALS4SLC2A1 | |
| SCHEMBL8831033 | 0.89 | MAPK1 (0.72) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL8831030 | 0.89 | MAPK1 (0.72) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974793-B2 | Methods and systems for inducing immunologic tolerance to non-self antigens | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-03-10 | — | — | US | disclosed |
| US-20120021056-A1 | Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021056-A1 | Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens | CD47, CD74, HLA-C | MAPK1 2294/4885LGALS8 34/4885LGALS3 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.